Learn about the use of antabuse in treating alcoholism. take the drug when they anticipate a high-risk situation or craving is about to occur. After your last dose of Antabuse, you may have adverse reactions to alcohol for up to two weeks, sometimes longer. If you're in a high-risk situation and you feel. Find a comprehensive guide to possible side effects including common and rare side effects when taking Antabuse (Disulfiram) for healthcare professionals and. Facts Speak Louder Than Words. Since that time he has published more than 20 op-eds in regional and national newspapers on different aspects of the crisis. Approximately 14 percent had drunk in the past but were no longer drinking. The drug does not cause tolerance and may be taken until long-term sobriety is maintained. With motivation and supervision, disulfiram and Antabuse can aid in recovery from alcoholism. They may perform a breathalyzer test, physical exam or a pregnancy test to ensure disulfiram use is safe. Ready to make a change? Drowsiness, tiredness, tingling in my feet, are further side effects. These cards may be available from the manufacturer. Food and Drug Administration warning, about the risks of the drug. Understanding this process helps antabues patients from drinking and increase their motivation to sustain sobriety. Treatment FAQs. The enzyme catalyzes the reaction, but not on its own. The drugs cause adverse reactions, such as sweating, chest pain and nausea, when consumed with alcohol. Related Pages Treatment.